MEPYRAMINE MALEATE 2% w/w
Mepisan® Cream contains Mepyramine Maleate 2% w/w which is a derivative of ethlenediamine with the actions and uses of the histamine H1- receptor antagonists Mepyramine Maleate has also been shown experimentally to possess local analgesic action.
Mepisan® Cream is used for relief of symptoms of hypersensitivity reactions and in pruritic skin disorders. It is used to relief itching and pain associated with insect bites and stings. It also relieves the irritation and pain of nettle rash. Mepisan® Cream is a useful first-aid dressing for sunburn, minor scalds and burns.
Mepyramine is contra-indicated in premature infants and neonates. In acute vesicular and exudative dermatoses. Use with occlusive dressings. Use on broken skin and in patients hypersensitive to Mepyramine in pregnancy and lactation.
DOSAGE AND ADMIMNISTRATION
Mepisan® Cream should be applied to the affected area two or three times daily for up to three days. Special care must be taken when large areas of broken skin are involved and application must be documented immediately if there is an adverse skin reaction due to sensitization to the product.
SIDE EFFECTS AND PRECAUTIONS
Topical therapy may produce hypersensitivity reactions. Particularly of the skin and cross-sensitivity to related drugs may occur. Skin sensitization, eczematous reactions and photosensitivity may develop after topical application. Systemic side-effects have been reported after topical application of antihistamines to large areas of the skin.
Mepisan® Cream is available as a smooth white/off-white homogeneous cream in 20g Tube for Topical use.